Why Low Norepinephrine Can Show Up as Body Aches

Understanding pain that doesn’t come from injury Many people experience ongoing aches, soreness, or “flu-like” body pain even when scans, labs, or exams look normal. This kind of pain is real, but it often reflects how the nervous system processes and amplifies signals rather than clear tissue damage (Clauw, 2015; Woolf, 2011). One key player …

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Norepinephrine, Pain, and the Overprotective Nervous System

When people talk about pain, we usually picture damaged tissue: a pulled muscle, an inflamed joint, something “wrong” in the body. But much of the pain that shows up in everyday life—diffuse aches, flu-like soreness, that heavy, leaden feeling—is not primarily about tissue damage. Instead, it reflects how the nervous system is calibrating threat and …

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